中国组织工程研究与临床康复2010,Vol.14Issue(33):6262-6266,5.DOI:10.3969/j.issn.1673-8225.2010.33.044
正畸力作用下炎性牙周组织的改建
Remodeling of inflammatory periodontal tissues during orthodontic tooth movement
祝军 1赵宏轶 2何苗 1英杰1
作者信息
- 1. 新疆医科大学附属中医医院口腔科,新疆维吾尔自治区乌鲁木齐市,830000
- 2. 新疆乌鲁木齐市第一人民医院分院口腔科,新疆维吾尔自治区乌鲁木齐市,830000
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摘要
Abstract
BACKGROUND: More and more patients with periodontal disease require orthodontic treatments. Thus, the remodeling process and its mechanism of inflammatory periodontal tissues become a hot point during orthodontic tooth movement.OBJECTIVE: To observe the remodeling of inflammatory periodontal tissues during orthodontic tooth movement.METHODS: A total of 50 Sprague Dawley rats were randomly divided into the control and periodontitis groups. In the periodontitis group, rats were established periodontitis models. After that, all rats were prepared for orthodontic tooth movement models. The remodeling of periodontal tissues was observed by hematoxylin-eosin staining at 1, 3, 5, 7 and 14 days after orthodontic tooth movement.RESULTS AND CONCLUSION: The movement distance of the periodontitis group was greater than that of the control group. At 0-7 days after orthodontic force application, there was obviously bone resorption at the pressure side and the bone formation was inhibited at the tension side; at 14 days after force application, the bone resorption was diminished, associated with large numbers of multinucleated osteoclasts at the pressure sides in both groups. The findings showed that rats with periodontitis suffered more periodontal traumatism during orthodontic tooth movement, thus, treatment should be delayed until the inflammatory signs were controlled and the local inflammatory was eliminated.关键词
牙周炎/正畸/牙移动/大鼠/组织构建分类
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祝军,赵宏轶,何苗,英杰..正畸力作用下炎性牙周组织的改建[J].中国组织工程研究与临床康复,2010,14(33):6262-6266,5.