国际医药卫生导报2010，Vol.16Issue(24)：3027-3029,3.DOI:10.3760/cma.j.issn.1007-1245.2010.24.028
血清PSA、ALP检测在前列腺癌骨转移诊断中的价值
The Application of Serum PSA ALP Measurement in Diagnosis of Bone Metastasis in Prostate Cancer Patients
龚兰 1吴瑜霞 1杨秀华 1陈振宇 1汤平 1莫云丹1
作者信息
摘要
Abstract
Objective To evaluate the clinical value of serum prostate-specific antigen(PSA)and alkaline phosphatase(ALP) measurement in the diagnosis of prostate cancer patients with hone metastasis.Methods Serum PSA and ALP levels in 123 cases of prostate cancer patients, during which 58 ones have bone metastasis and the others do not have bone metastasis, was retrospectively analyzed to find the correlation between serum PSA ,ALP and bone metastasis. And use the bone scan as the diagnosis golden standard for bone metastasis. Results Both serum PSA and ALP levels in bone metastases patients were higher than the patients without bone metastases( P<0.05 ). The bone metastases incidence rate(45.5%) of the prostate cancer patients with a serum PSA ≥ 20 ug/L was higher than the incidence rate(1.63%) of the ones with serum PSA<20ug/L; the ones with a serum ALP ≥ 90 U/L which counted for 39.02% had a higher incidence rate of bone metastases than the ones with a serum ALP<90 U/L which counted for 8.13%.Conclusion For the definite prostate cancer patients without any treatment, to diagnose the bone metastasis early, nuclide bone scan is suggested as a routine detection, if the serum PSA ≥ 20 ug/L or the serum ALP ≥ 90 U/L.关键词
前列腺癌/骨转移/前列腺特异抗原/碱性磷酸酶Key words
prostate cancer/bone metastasis: prostate-specific antigen/alkaline phosphatase分类
医药卫生引用本文复制引用
龚兰,吴瑜霞,杨秀华,陈振宇,汤平,莫云丹..血清PSA、ALP检测在前列腺癌骨转移诊断中的价值[J].国际医药卫生导报,2010,16(24):3027-3029,3.
