国际医药卫生导报2010，Vol.16Issue(24)：2967-2969,3.DOI:10.3760/cma.j.issn.1007-1245.2010.24.005
鼻咽癌放射治疗后诱发的第二恶性肿瘤的临床特点分析
Clinical characteristics of second primary carcinoma induced by radiation therapy for nasopharyngeal carcinoma
潘智灵 1杨湘宁 1姚良忠 1陈万楷 1王培1
作者信息
- 1. 510080,广州,广东药学院附属第一医院耳鼻喉科
- 折叠
摘要
Abstract
Objective To investigate the clinical characteristics of second primary carcinoma induced by radiation therapy in patients with nasopharyngeal carcinoma. Methods A retrospective analysis was carried out to investigate the clinical data of radiation-induced second primary carcinoma in 28 cases with nasopharyngeal carcinoma. Results Among 28 cases, 16 (57.1%) cases presented squamous cell carcinoma; 5 (17.9%) cases presented sarcoma; 3 (10.7%) presented adenoid cystic carcinoma; another 3 (10.7%) presented basal cell carcinoma; and 1( 3.6%)presented malignant melanoma. In 20 cases that accepted surgical treatment, the 3-year, and 5-year survival rate were 75% and 35%; the 3-year survival rate after radiation therapy combined with chemotherapy was 25%; those with only radiotherapy or chemotherapy were all dead in 2 years. Conclusions If a patient with radiation-induced second primary carcinoma has an indication for surgery, it' s better to use treatment such as surgery or comprehensive treatment. The positive treatment to second primary carcinoma can also get good curative effect.关键词
鼻咽癌/放射治疗/第二原发癌/临床Key words
Nasopharyngeal carcinoma/Radiotherapy/Second primary carcinoma/Clinical分类
医药卫生引用本文复制引用
潘智灵,杨湘宁,姚良忠,陈万楷,王培..鼻咽癌放射治疗后诱发的第二恶性肿瘤的临床特点分析[J].国际医药卫生导报,2010,16(24):2967-2969,3.
