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窄谱中波紫外线联合他扎罗汀凝胶治疗寻常型银屑病疗效观察

张忠华 赵梓纲 丁香玉 解方 樊建峰 冯峥

军医进修学院学报2011,Vol.32Issue(2):153-154,162,3.
军医进修学院学报2011,Vol.32Issue(2):153-154,162,3.

窄谱中波紫外线联合他扎罗汀凝胶治疗寻常型银屑病疗效观察

Effect of combined narrow band ultraviolet B and tazarrotene gel on psoriasis vulgaris

张忠华 1赵梓纲 2丁香玉 2解方 2樊建峰 2冯峥2

作者信息

  • 1. 秦皇岛市第三医院,变态反应科,河北,秦皇岛,066000
  • 2. 解放军总医院,皮肤科,北京,100853
  • 折叠

摘要

Abstract

Objective To study the efficacy and safety of combined narrow band-ultraviolet B(NB-UVB) and tazarrotene gel in treatment of psoriasis vulgaris. Methods Two hundred and forty patients with psoriasis vulgaris were divided into groups A, B and C, 80 patients in each group. Patients in group A were treated with combined NB-UVB radiation(once a day) and topical tazarrotene gel cream in the evening. Patients in group B were treated with topical tazarrotene gel cream in the evening, and patients in group C received treatment with NB-UVB radiation, once every other day for 8 weeks. Results The effective rate was 82.9%, 62.8% and 73.3% for the 3 groups, respectively. The distinction of PASI score in 3 groups was significantly different before and after treatment (P<0.05). The effective rate of combined NB-UVB radiation and topical tazarrotene gel cream was the highest followed by that of topical tazarrotene gel and NB-UVB radiation(P<0.05). Only mild erythemas and itching were observed in the 3 groups during the treatment and no severe side effect occurred. Conclusion Combined NB-UVB and tazarrotene gel is effective and safe in treatment of psoriasis vulgaris.

关键词

紫外线/银屑病/他扎罗汀/治疗

Key words

Ultraviolet Rays/ Psoriasis/ Tazarrotene Gel/ Therapy

分类

医药卫生

引用本文复制引用

张忠华,赵梓纲,丁香玉,解方,樊建峰,冯峥..窄谱中波紫外线联合他扎罗汀凝胶治疗寻常型银屑病疗效观察[J].军医进修学院学报,2011,32(2):153-154,162,3.

军医进修学院学报

OACSTPCD

2095-5227

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