中国药房2011，Vol.22Issue(2)：149-151,3.
卡络磺钠注射液与注射用加替沙星的配伍稳定性考察
Study on the Compatibility of Carbazochrome Sodium Sulfonate Injection and Gatifloxacin for Injection
朱雪松 1熊秋菊 1郑芳 1李鹏1
作者信息
- 1. 郧阳医学院附属东风医院药剂部,十堰市,442008
- 折叠
摘要
Abstract
OBJECTIVE: To study the compatibility of Carbazochrome sodium sulfonate injection and Gatifloxacin for injection in 0.9％ sodium chloride injection. METHODS: Carbazochrome sodium sulfonate injection was combined with gatifloxacin for injection in 0.9％ sodium chloride injection. The contents of carbazochrome sodium sulfonate and gatifloxacin in mixture were determined by RP-HPLC-DAD at 25 ℃ or 37 ℃ within 12 h and external appearance and pH were observed. RESULTS: There was no significant change in appearance, pH and the content of carbazochrome sodium sulfonate and gatifloxacin under two temperature conditions within 12 h. CONCLUSION: Carbazochrome sodium sulfonate injection combined with gatifloxacin for injection in 0.9％ sodium chloride injection can be used within 12 h at 25 ℃ and 37 ℃.关键词
反相高效液相色谱法/二极管阵列检测器/卡络磺钠/加替沙星/配伍/稳定性分类
医药卫生引用本文复制引用
朱雪松,熊秋菊,郑芳,李鹏..卡络磺钠注射液与注射用加替沙星的配伍稳定性考察[J].中国药房,2011,22(2):149-151,3.
