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HPLC法测定清开灵泡腾片中栀子苷的含量

笔雪艳 刘晓凤 张清波

中国药房2011,Vol.22Issue(3):240-241,2.
中国药房2011,Vol.22Issue(3):240-241,2.

HPLC法测定清开灵泡腾片中栀子苷的含量

Content Determination of Geniposide in Qingkailing Effervescent Tablets by HPLC

笔雪艳 1刘晓凤 2张清波1

作者信息

  • 1. 黑龙江省食品药品检验检测所,哈尔滨市,150001
  • 2. 黑龙江中医药大学,哈尔滨市,150040
  • 折叠

摘要

Abstract

OBJECTIVE: To establish the method for the content determination of geniposide in Qingkailing effervescent tablets. METHODS: HPLC was adopted. The separation was performed on Agilent C18( 150 mm×4.6 mm, 5 μm) column with acetonitrile-water (11:89) as mobile phase. The detection wavelength was set at 238 mn. The flow rate was 1.0 mL·min-1. RESULTS: The linear range of geniposide was 0.030 12-0.903 60 μg(r=0.999 9) With an average recovery of 97.02% (RSD=1.0% ,n=6). CONCLUSION: The method is simple, accurate and well-separated for the quality control of Qingkailing effervescent tables.

关键词

清开灵泡腾片/栀子苷/高效液相色谱法/含量测定

分类

医药卫生

引用本文复制引用

笔雪艳,刘晓凤,张清波..HPLC法测定清开灵泡腾片中栀子苷的含量[J].中国药房,2011,22(3):240-241,2.

基金项目

《中国药典》2010版(一部)标准研究课题(2H-408-414) (一部)

中国药房

OACSCDCSTPCD

1001-0408

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