中国药房2011，Vol.22Issue(7)：644-645,2.
灵菊七抗氧化成分研究
Antioxidant Constituents of Gynura medica
伏晓 1周寿然 2万春鹏2
作者信息
- 1. 河南省中医院药剂科,郑州市,450002
- 2. 江西中医学院基础医学院,南昌市,330006
- 折叠
摘要
Abstract
OBJECTIVE: To study the antioxidant constituents phenol extracts of Gynura medica. METHODS: The antioxidant part of G. medica was successively isolated by DPPH antioxidant model using systematic solvent extraction. The chemical constituents of antioxidant fraction were isolated and purified by silica gel, Sephadex LH-20 and RP-ODS column chromatography. Their chemical structures were identified by physicochemical properties and spectral analysis. RESULTS: The ethyl acetate fraction exhibited the strongest antioxidant activity compared with other fractions of G. medica extract. 4 phenolic constituents were isolated and identified as kaempferol ( 1 ), astragalin (2), caffeic acid (3) and 3, 4-dicaffeoylquinicacid. All of the phenolic constituents were isolated from this plant for the first time and compounds 3 and 4 were isolated from the genus of Gynura for the first time. CONCLUSION: The results provide the scientific basis for further exploitation of G. medica plant.关键词
三七草属/灵菊七/抗氧化/酚类成分分类
医药卫生引用本文复制引用
伏晓,周寿然,万春鹏..灵菊七抗氧化成分研究[J].中国药房,2011,22(7):644-645,2.
