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复方苦参注射液联合放射治疗晚期骨转移疼痛的临床观察

王嵘 易敏 潘贤英

中国药房2011,Vol.22Issue(4):329-331,3.
中国药房2011,Vol.22Issue(4):329-331,3.

复方苦参注射液联合放射治疗晚期骨转移疼痛的临床观察

Clinical Observation of Compound Matrine Injection Combined with Radiotherapy for Advanced Metastatic Bone Pain

王嵘 1易敏 2潘贤英1

作者信息

  • 1. 青海省肿瘤医院放疗科,西宁市,810007
  • 2. 青海省肿瘤医院病理科,西宁市,810007
  • 折叠

摘要

Abstract

OBJECTIVE: To study the therapeutic efficacy and adverse drug reactions of combination therapy for advanced metastatic bone pain.METHODS: A total of 78 patients with metastatic bone cancer admitted in our hospital were randomly divided into control group (38 cases) and treatment group (40 cases).Radiotherapy (DT 30 GY, ten times) was adopted in control group,while Compound matrine injection (20 mL, once a day, ten times) was used in treatment group on the basis of radiotherapy.The odynolysis efficiency, KPS and adverse drug reaction were compared between 2 groups.RESULTS: Compared with the control group, the odynolysis efficiency of treatment group was obviously increased, there was significant difference between 2 groups (P<0.01); the KPS of treatment group was higher than control group, there was significant difference between 2 groups (P<0.01).No serious adverse drug reaction was found between 2 groups.CONCLUSION: Compound matrine injection and radiotherapy has obvious cooperative effect in the treatment of advanced metastatic pain, which improve the KPS score of patient significantly.

关键词

复方苦参注射液/放射治疗/骨转移

分类

医药卫生

引用本文复制引用

王嵘,易敏,潘贤英..复方苦参注射液联合放射治疗晚期骨转移疼痛的临床观察[J].中国药房,2011,22(4):329-331,3.

中国药房

OACSCDCSTPCD

1001-0408

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