中国药房2011，Vol.22Issue(7)：586-588,3.
泰山沙棘果提取物调血脂作用研究
Study on Regulating Blood Lipid Effect of the Extracts of Taishan Hippophae rhamnoides Fruits
张颖 1张立木 2秦树存 1李同德 1彭吉星1
作者信息
- 1. 泰山医学院动脉粥样硬化研究所,泰安市,271000
- 2. 泰安市第一人民医院,泰安市,271000
- 折叠
摘要
Abstract
OBJECTIVE:To explore the effect of the ethanol extract and water extract of Hippophae rhamnoides fruits on regulating blood lipid in hyperlipemia mice. METHODS: Normal control group was treated with common diet, experimental hyperlipemia mice were model group. The hyperlipemia mice were raised with ethanol extract and water extract of H. rhamnoides fruits at the dose of 1 000, 500 and 250 mg·kg-1 as experiment group. The levels of total chholesterin(TC),triglyeride (TG),high lipoprotein cholesterol (HDL-C) in serum were all tested. RESULTS: The level of TC and TG in model group were higher than in normal control group(P＜0.01).Compared with model group, the level of the TC decreased significantly in the different dose ethanol extract of H. rhamnoides fruits group (P＜0.01). The level of TG decreased significantly in different dose of ethanol extract and water extract of H. rhamnoides fruits (P＜0.05 or P＜0.01), and it was not obvious effect on the level of HDL-C in serum. CONCLUSION: The extracts of H. rhamnoides fruits have significantly effects on regulating blood lipid. It can prevent and cure the hyperlipemia.关键词
沙棘果/胆固醇/甘油三酯/高密度脂蛋白/高脂血症分类
医药卫生引用本文复制引用
张颖,张立木,秦树存,李同德,彭吉星..泰山沙棘果提取物调血脂作用研究[J].中国药房,2011,22(7):586-588,3.
