烟台大学学报（自然科学与工程版）2011，Vol.24Issue(1)：27-33,7.
132-羟基脱镁叶绿酸-a甲酯的合成及其立体结构的表征与确定
Synthesis of Methyl 132-Hydroxylpheophorbide-a and Characterization and Identification of Their Stereostructure
摘要
Abstract
Chlorophyll-α is used as starting material and comnverted into methyl pyropheophorbide-a by trans esterification and removement of metal ion. 132 ( R/S) -132-hydroxylpheophorbide-α as a mixture is obtained by allomerization in heat acetic acid. The purpurin-18 methyl ester as a major oxidized and rearranged product is produced by air-oxidation in methanolic potassium hydroxide. The diastereoisomers are separated by column chromatography and stereostructures are characterized and identified by 1 H NMR spectra.关键词
叶绿素-a/二氢卟吩/脱镁叶绿酸-a甲酯/立体化学/表征分类
化学化工引用本文复制引用
张千,姚楠楠,武进,王进军..132-羟基脱镁叶绿酸-a甲酯的合成及其立体结构的表征与确定[J].烟台大学学报（自然科学与工程版）,2011,24(1):27-33,7.基金项目
山东省自然科学基金资助项目(Y2008B49). （Y2008B49）
