癌症2011，Vol.30Issue(2)：114-119,6.
The prevalence and prevention of nasopharyngeal carcinoma in China
The prevalence and prevention of nasopharyngeal carcinoma in China
Su-Mei Cao 1Malcolm J. Simons 2Chao-Nan Qian3
作者信息
- 1. State Key Laboratory of Oncology in South China, Guangzhou, Guangdong 510060, P. R. China
- 2. Department of Epidemiology, Clinical Trial Study Center, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China
- 3. Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, Guandong 510060, P. R. China
- 折叠
摘要
Abstract
Nasopharyngeal carcinoma (NPC) has remarkable epidemiological features, including regional, racial,and familial aggregations. The aim of this review is to describe the epidemiological characteristics of NPC and to propose possible causes for the high incidence patterns in southern China. Since the etiology of NPC is not completely understood, approaches to primary prevention of NPC remain under consideration. This situation highlights the need to conduct secondary prevention, including improving rates of early detection, early diagnosis, and early treatment in NPC patients. Since the 1970's, high-risk populations in southern China have been screened extensively for early detection of NPC using anti-Epstein-Barr virus (EBV) serum biomarkers. This review summarizes several large screening studies that have been conducted in the high-incidence areas of China. Screening markers, high-risk age range for screening,time intervals for blood re-examination, and the effectiveness of these screening studies will be discussed.Conduction of prospective randomized controlled screening trials in southern China can be expected to maximize the cost-effectiveness of early NPC detection screening.关键词
Nasopharyngeal carcinoma/ epidemiology/ screeningKey words
Nasopharyngeal carcinoma/ epidemiology/ screening引用本文复制引用
Su-Mei Cao,Malcolm J. Simons,Chao-Nan Qian..The prevalence and prevention of nasopharyngeal carcinoma in China [J].癌症,2011,30(2):114-119,6.
