西北国防医学杂志2011，Vol.32Issue(1)：27-29,3.
高功率微波辐照对大鼠肝脏形态学及血清氧自由基的影响
Effect of high power microwave on the morphological changes of rats' liver and oxygen-derived free radicals in the blood serum
张兵华 1费晋秀 1郭永博 1王红霞 1宋晓峰 1闻勤生 2黄裕新2
作者信息
- 1. 解放军323医院干二科,陕西,西安,710054
- 2. 第四军医大学唐都医院消化科
- 折叠
摘要
Abstract
Objective:To observe the morphological changes of rats' liver and oxygen - derived free radicals in the blood serum after exposing to different pulses of high power microwave (HPM). Methods: SD rats were eradiated with 10,000 ( group Ⅰ ), 100,000 ( group Ⅱ ) and 400,000 ( group Ⅲ) pulses of HPM respectively. After morphology observation, the patho - histological changes of liver were investigated through biological microscope and electroscope. The changes of superoxide dismutase(SOD) and malondialdehyde(MDA) in blood serum were detected by biochemical method. Results: There were some changes in the liver of group Ⅲ, such as the dilatation of capillary, bleeding on the surface of liver. The ultrastructure changes of liver were most serious in the group Ⅲ.Compared with the control group, the level of serum SOD was decreased (P ＜0.01 ), while MDA increased (P ＜0.01 ), especially in group Ⅲ. Conclusion: HPM has significant damage on the liver. The injury mechanism of HPM may be involved with the oxygen free radical in the blood serum.关键词
高功率微波/超氧化物歧化酶/丙二醛/氧自由基/大鼠分类
医药卫生引用本文复制引用
张兵华,费晋秀,郭永博,王红霞,宋晓峰,闻勤生,黄裕新..高功率微波辐照对大鼠肝脏形态学及血清氧自由基的影响 [J].西北国防医学杂志,2011,32(1):27-29,3.
