南京农业大学学报2011，Vol.34Issue(1)：89-94,6.
丙酮酸肌酸对肉鸡脂肪代谢和蛋白质代谢的影响
Effects of creatine pyruvate on lipid and protein metabolism in broiler chickens
摘要
Abstract
Three hundreds 1 day-old male AA broilers were randomly divided into four groups, and each gnoup included three replicates with 25 broilers. Creatine pyruvate(CrPyr) was not added in the basal feed( control group). The low,middle and high CrPyr treated groups were fed with the basal feed with the supplementation of 1％ ,5％ and 10％ from 1 to 42 day-old,respeclively. Four broiler chickens per replicate from each treatmcnt were chosen randomly and slaughtered to collect specimens of blood, liver, abdominal fat,left breast and leg muscle samples at 42 day-old. The content of blood glucose(BG), triglycerides (TG), total cholesterol ( TC ), high density lipoprotein-cholesterol ( HDL-C ), low density lipoprotein-cholesterol ( LDL-C ), creatine kinease ( CK),uric acid(UA) , triiodothyrunine( T3 ) , thyroxin ( T4 ), free triiodothyronine ( FT3) , free thyroxin ( FT4 ) , glucagon, insulin, leptin and the content of nucleic acid and protein in muscle were detected. The results showed that CrPyr significantly decreased the percentage of abdominal fat weight and the concentrations of TG,LDL-C and UA in liver and serum,but it obviously increased serum FT3 value, and unchanged BC and TC levels. The relative pectoral muscle weight,the protein content of leg muscle and the RNA/DNA ratio of CrPyr-administered groups were significantly higher than those of control group. CrPyr also elevated the expressions of IGF-I and myogenin mRNA in muscle. The findings suggest that CrPyr regulates lipid metabolism of broilers by enhancing the enzyme activity and hormone levels related to lipolysis. Also CrPyr may improve the muscle growth by elevating the synthesis of protein in broilers.关键词
丙酮酸肌酸/肉鸡/脂肪代谢/蛋白质代跗Key words
creatine pyruvate/ broilet/ lipid metabolism/ protein metabolism分类
农业科技引用本文复制引用
王曼,陈娟,孔一力,马海田,邹思湘..丙酮酸肌酸对肉鸡脂肪代谢和蛋白质代谢的影响[J].南京农业大学学报,2011,34(1):89-94,6.基金项目
国家自然科学基金项目(30600439) （30600439）
