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羊膜移植及5-氟尿嘧啶联合小梁切除术治疗原发性青光眼的临床观察

刘馨 徐军 李佳 刘丹

重庆医学2011,Vol.40Issue(6):583-584,2.
重庆医学2011,Vol.40Issue(6):583-584,2.DOI:10.3969/j.issn.1671-8348.2011.06.028

羊膜移植及5-氟尿嘧啶联合小梁切除术治疗原发性青光眼的临床观察

Amniotic membrane transplantation with trabeculectomy and 5-FU for the treatment of primary glaucoma

刘馨 1徐军 2李佳 1刘丹1

作者信息

  • 1. 辽宁医学院附属第一医院,检验科,锦州,121000
  • 2. 辽宁医学院附属第一医院,眼科,锦州,121000
  • 折叠

摘要

Abstract

Objective To explore the effects and securities of amniotic membrane transplantation with trabeculectomy and 5 FU for the treatment of primary glaucoma. Methods Amniotic membrane transplantation with trabeculectomy and 5 FU were used to treatment primary glau coma chamber depth, and the complications of operation were studied on 28 cases (32 eyes) of primary glaucoma. All the cases were followed-up for 6-24 months. The IOP,visual acuity,filtering bleb anterior chamber depth,and the complications of operation were studied. Results The IOP was decreased from (39.14±5.67)mm Hg preoperatively to (16.28±3.18) mm Hg postoperatively(P<0.01). The total success rate was 96.9 %. 29 eyes (91%) maintained functional filtering bleb, visual decline didn't appear in all cases, the complications included shallow anterior chamber (1 eyes), early postoperative hypotony (2 eyes) and corneal edema(5 eyes), which returned to normal after I week of operation. Conclusion Amniotic membrane transplanta tion with trabeculectomy and 5-FU for the treatment of primary glaucoma can effectively inhibit the scar formation,decrease complications and increase the success rate considerably. The method is safe and effective in the management of primary glaucoma.

关键词

羊膜移植/原发性青光眼/小梁切除术/5-氟尿嘧啶

Key words

trabeculectomy/ glaucoma/ amniotic membrane transplantation/ 5-fluorouracil

引用本文复制引用

刘馨,徐军,李佳,刘丹..羊膜移植及5-氟尿嘧啶联合小梁切除术治疗原发性青光眼的临床观察[J].重庆医学,2011,40(6):583-584,2.

重庆医学

OA北大核心CSCDCSTPCD

1671-8348

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