重庆医学2011,Vol.40Issue(4):362-363,365,3.DOI:10.3969/j.issn.1671-8348.2011.04.022
双黄连注射剂不良反应及其影响因素回顾性调查
Retrospective investigation of ADR caused by shuanghuanglian injection and influential factors
摘要
Abstract
Objective To investigate the incidence rates, types and influential factors of adverse drug reactions (ADR) of shuanghuanglian injection, to provided the scientific evidence for the safety evaluation of shuanghuanglian injection and guide application in clinical. Methods The patients used shuanghuanglian injection were investigated by cluster sampling, and the ADR of shuanghuanglian injection and influential factors were analyzed by case retrospective study. Results The incidence rate of ADR was 2.56 %, the main ADR of shuanghuanglian injection was allergic reactions. The ADR rate in male was significantly higher than that in female(P<0.05). The medication days,medication dosage and drug combination had significant influence(P<0.05). Conclusion Medical staff should pay attention to rational medication in clinical to decrease the incidence rate of ADR and to improve security of use of drug.关键词
双黄连注射剂/数据收集/不良反应/影响因素Key words
shuanghuanglian injection/ data collection / adverse drug reaction / influential factors引用本文复制引用
程光文,曾婧,毛宗福,韩定芬,李汝霖..双黄连注射剂不良反应及其影响因素回顾性调查[J].重庆医学,2011,40(4):362-363,365,3.基金项目
湖北省教育厅科研基金重点项目(D200611007). (D200611007)