分析测试学报2011，Vol.30Issue(1)：81-84,4.DOI:10.3969/j.issn.1004-4957.2011.01.017
气相色谱-质谱法测定化妆品中的丙烯腈
Determination of Acrylonitrile in Cosmetics by GC -MS Method
刘茜 1马强 1席海为 1王烨 1白桦 1王超1
作者信息
- 1. 中国检验检疫科学研究院,北京,100123
- 折叠
摘要
Abstract
A gas chromatography - mass spectrometric method was developed for the determination of acrylonitrile in cosmetic samples. The cosmetics were ultrasonically extracted with methanol and then centrifuged. The concentrated supernatant was purified with an Oasis HLB solid phase extraction cartridge using 20％ methanol solution as washing agent and 80％ methanol solution as eluting agent.The eluent was further dehydrated with anhydrous sodium sulphate. The analysis was carried out with a capillary column( HP-INNOWax 60 m ×0. 25 mm x0. 50 μm) under electron ionization conditions at a flow rate of 1.2 mL/min. The quantitation was performed by the external standard method under selected ion monitoring (SIM) mode using monitering ions of m/z 53, 52 and 26. The recoveries were in the range of 84％ - 101％ with relative standard deviations(RSDs) of 1.1％ -4. 2％. The detection limit was 0. 4 mg/kg. This method was proved to be simple, accurate, and was suitable for the determination of aerylonitrile in cosmetics.关键词
化妆品/丙烯腈/固相萃取/气相色谱-质谱法Key words
cosmetics/ acrylonitrile/ solid phase extraction/ gas chromatography -mass spectrometry分类
化学化工引用本文复制引用
刘茜,马强,席海为,王烨,白桦,王超..气相色谱-质谱法测定化妆品中的丙烯腈[J].分析测试学报,2011,30(1):81-84,4.
