无机材料学报2011，Vol.26Issue(1)：43-48,6.DOI:10.3724/SP.J.1077.2011.00043
预处理对构建丝素蛋白纤维/磷灰石仿生骨修复材料的影响
Effect of Pretreatment on Fabrication of Natural Fibroin Fiber/Apatite Composites Using Alternate Soaking Method
摘要
Abstract
To develop biomimetic fibroin/apatite composites with bone-like structure by alternate soaking method,the degummed natural fibroin fibers were pretreated by soaking into CaCl2：EtOH：H2O (n(CaCl2)：n(EtOH)：n(H2O)= 12：8) solution for given time and then soaked into calcium solution and phosphate solution, respectively, to fabricate fib roin/apatite composites. The effects of pretreatment time and the alternate soaking times on fibroin microstructure and fibroin/apatite composites were examined by SEM, FTIR, XRD and TGA techniques. The pretreatment using CaCl2：EtOH：H2O(n(CaCl2)：n(EtOH)：n(H2O)= 1:2:8) solution makes fibroin fiber exhibit rougher surface and higher internal porosity, which is beneficial to interaction of calcium ion and residue groups such as -COOH, -OH and -CONH- from fibroin, and then improve the deposition of apatite on fibroin fibers. The homogeneous apatites with oriented c-axis were formed on the pretreated fibroin fibers. Moreover, there are more than 30wt％ apatites deposited on fibroin fibers after altemate soaking for more than 3 times. The fibroin/apatite composite has potential to be applied as bone repair materials.关键词
丝素蛋白纤维/磷灰石/生物矿化分类
信息技术与安全科学引用本文复制引用
程新,李延报,陆春华,李东旭,许仲梓..预处理对构建丝素蛋白纤维/磷灰石仿生骨修复材料的影响[J].无机材料学报,2011,26(1):43-48,6.基金项目
国家自然科学基金(50802042) （50802042）
江苏省自然科学基金(BK2008379) （BK2008379）
材料化学工程国家重点实验室开放基金(KL09-6) （KL09-6）
