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糖化血红蛋白不同测定方法的一致性评价

曾宪飞 谈昀 李军民 王小刚

现代检验医学杂志2011,Vol.26Issue(1):67-68,71,3.
现代检验医学杂志2011,Vol.26Issue(1):67-68,71,3.DOI:10.3969/j.issn.1671-7414.2011.01.024

糖化血红蛋白不同测定方法的一致性评价

Analysis on the Agreement of HbA1c Determined by Two Methods

曾宪飞 1谈昀 1李军民 1王小刚1

作者信息

  • 1. 武警陕西省总队医院检验科,西安,710054
  • 折叠

摘要

Abstract

Objective To assess the agreement of detecting HbAle in whole blood by boronic acids affinity chromatography and ion exchange chromatography. Methods The HbAle of the same sample was determined by the two methods and the results classed into three levels (< 7. 5 % , 7. 5 %~ 11. 5% , > 11. 5% ). BlandAltman analysis and Pearson ' s correlation were performed to evaluate the relationships between the results in same level. In BlandAltman plot the agreement of two methods was decided by the limits of agreement. Results Pearson's correlation analysis showed that the HbAle resulting from different methods presented good correlation. However,in level >11. 5% BlandAltman analysis indicated that there was significantbias. Conclusion In high concentration level.the detecting results using two different methods were not consistent. With respect to evaluating the agreement of uantitative data.the BlandAltman analvsis was more reliable than Pearson ' s correlation analysis.

关键词

糖化血红蛋白/一致性/Bland-Altman分析

分类

医药卫生

引用本文复制引用

曾宪飞,谈昀,李军民,王小刚..糖化血红蛋白不同测定方法的一致性评价[J].现代检验医学杂志,2011,26(1):67-68,71,3.

现代检验医学杂志

OACSTPCD

1671-7414

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