现代检验医学杂志2011,Vol.26Issue(1):67-68,71,3.DOI:10.3969/j.issn.1671-7414.2011.01.024
糖化血红蛋白不同测定方法的一致性评价
Analysis on the Agreement of HbA1c Determined by Two Methods
曾宪飞 1谈昀 1李军民 1王小刚1
作者信息
- 1. 武警陕西省总队医院检验科,西安,710054
- 折叠
摘要
Abstract
Objective To assess the agreement of detecting HbAle in whole blood by boronic acids affinity chromatography and ion exchange chromatography. Methods The HbAle of the same sample was determined by the two methods and the results classed into three levels (< 7. 5 % , 7. 5 %~ 11. 5% , > 11. 5% ). BlandAltman analysis and Pearson ' s correlation were performed to evaluate the relationships between the results in same level. In BlandAltman plot the agreement of two methods was decided by the limits of agreement. Results Pearson's correlation analysis showed that the HbAle resulting from different methods presented good correlation. However,in level >11. 5% BlandAltman analysis indicated that there was significantbias. Conclusion In high concentration level.the detecting results using two different methods were not consistent. With respect to evaluating the agreement of uantitative data.the BlandAltman analvsis was more reliable than Pearson ' s correlation analysis.关键词
糖化血红蛋白/一致性/Bland-Altman分析分类
医药卫生引用本文复制引用
曾宪飞,谈昀,李军民,王小刚..糖化血红蛋白不同测定方法的一致性评价[J].现代检验医学杂志,2011,26(1):67-68,71,3.