山西医科大学学报2011，Vol.42Issue(2)：149-151,3.DOI:10.3969/J.ISSN.1007-6611.2011.02.015
灼口综合征患者心理健康状况与血清IL-6、TNF-α水平的关系
Correlation of psychological profiles with serum levels of IL-6, TNF-α in patients with burning mouth syndrome
摘要
Abstract
Objective To explore the correlation of psychological profiles with serum levels of IL-6, TNF-α in patients with burning mouth syndrome. Methods Twenty-two patients first diagnosed as BMS were enrolled ( 19 females and 3 males ). Twenty- normal subjects were chosen as controls with similar age and sex. The fasting blood of 2 ml was drawn from the subjects under restine conditions in the morning to examine the serum levels of IL-6 and TNF-α by ELISA. SCL-90 was used to evaluate the psychological profiles. Results Compared with controls, the serum level of IL-6 significantly decreased in BMS patients( P ＜ 0.05 ), but the level of TNF-α had no significant change( P ＞ 0.05 ). The scores of SCL-90 were significantly higher in BMS patients than those in the controls ( P ＜ 0.05 ).SCL-90 scores were higher in the premenopausal women than that in postmenopausal women, and there was significant difference in somatization,anxiety and hostile between them( P ＜ 0.05 ). The psychological profiles were not correlated to serum levels of IL-6 and TNF-α. Conclusion The psychogenic factors exert very important roles in the development of BMS, but psychological profiles are not correlated to serum levels of IL-6 and TNF-α.关键词
灼口综合征/精神因素/IL-6/TNF-α分类
医药卫生引用本文复制引用
管翠强,焦艳军,武云霞..灼口综合征患者心理健康状况与血清IL-6、TNF-α水平的关系[J].山西医科大学学报,2011,42(2):149-151,3.基金项目
山西省高等学校科技项目(20091177) （20091177）
