生殖医学杂志2011,Vol.20Issue(1):73-77,5.DOI:10.3969/j.issn.1004-3845.2011.01.021
DEAD box家族蛋白与精子生成的研究进展
Update of studies on DEAD-box protein family and spermatogenesis
摘要
Abstract
The normal development and maturation of sperm need not only a variety of related gene expressions, but also the participation of a variety of RNAs.These RNAs are required to have a better stability to maintain their functions.DEAD-box protein family is an ATP-dependent RNA helicase family that is found to be involved in a variety of RNA metabolic processes such as RNA secondary structure transformation, transcription initiation, mitochondrial RNA splicing, ribosome and spliceosome assembly,mRNA degradation, and the maintenance of mRNA stability.Recent studies have shown that some members of this family including DDX3, DDX4, DDX25 and others, are closely related to spermatogenesis.关键词
DEAD-box家族蛋白/基因/精子生成引用本文复制引用
胡秀玉,彭弋峰..DEAD box家族蛋白与精子生成的研究进展[J].生殖医学杂志,2011,20(1):73-77,5.基金项目
国家科技部生殖健康基础研究(G1999055905)子课题 (G1999055905)