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DEAD box家族蛋白与精子生成的研究进展

胡秀玉 彭弋峰

生殖医学杂志2011,Vol.20Issue(1):73-77,5.
生殖医学杂志2011,Vol.20Issue(1):73-77,5.DOI:10.3969/j.issn.1004-3845.2011.01.021

DEAD box家族蛋白与精子生成的研究进展

Update of studies on DEAD-box protein family and spermatogenesis

胡秀玉 1彭弋峰1

作者信息

  • 1. 皖南医学院弋矶山医院生殖医学研究所,安徽芜湖,241001
  • 折叠

摘要

Abstract

The normal development and maturation of sperm need not only a variety of related gene expressions, but also the participation of a variety of RNAs.These RNAs are required to have a better stability to maintain their functions.DEAD-box protein family is an ATP-dependent RNA helicase family that is found to be involved in a variety of RNA metabolic processes such as RNA secondary structure transformation, transcription initiation, mitochondrial RNA splicing, ribosome and spliceosome assembly,mRNA degradation, and the maintenance of mRNA stability.Recent studies have shown that some members of this family including DDX3, DDX4, DDX25 and others, are closely related to spermatogenesis.

关键词

DEAD-box家族蛋白/基因/精子生成

引用本文复制引用

胡秀玉,彭弋峰..DEAD box家族蛋白与精子生成的研究进展[J].生殖医学杂志,2011,20(1):73-77,5.

基金项目

国家科技部生殖健康基础研究(G1999055905)子课题 (G1999055905)

生殖医学杂志

OACSTPCD

1004-3845

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