实用医学杂志2011，Vol.27Issue(4)：637-639,3.DOI:10.3969/j.issn.1006-5725.2011.04.035
艾滋病合并卡氏肺孢子虫肺炎107例
Acquired immune deficiency syndrome complicated by pneumocystis carinii pneumonia: report of 107 cases
彭平 1唐小平 1胡中伟 1邓西龙 1郭家伟 1童裕维1
作者信息
摘要
Abstract
Objective To approach the diagnosis and treatment on acquired immune deficiency syndrome (AIDS) complicated by pneumocystis carinii pneumonia (PCP). Methods 107 patients complicated by PCP in 432 cases of AIDS who were hospitalized in the infectious department of our hospital during June 2009 to May 2010 were retrospectively analyzed. Results 85 patients had fever, cough, sputum or dyspnea; There were 16 cases whose arterial oxygen pressure were under 70 mmHg; Lactic dehydrogenase (LDH) was higher than normal in 91 cases; Chest radiography revealed increasing、thickening and/or ground glass-like changes in 67 cases, pulmonary nodules or patchy shadows in 36 cases, normal chest in 3 cases, hydropneumothorax in 1 case; CD4+ T cells was less than 50 cells/uL in 86 cases. 19 cases were found pneumocystis carinii, almost all were clinical diagnosed. The treatment with sulfamethoxazole (SMZ) had been for 21 days, 93 cases were cured, 12 cases died, and 2 cases were converted to ICU. Conclusions The gold standard to diagnose PCP is finding the pathogen. Its detection rate is low, the current clinical diagnosis is still based. The incidence of AIDS complicated by PCP is high, particularly in whose CD4+ T cells was less than 50 cells/μL. The AIDS patients should be given highly active antiretroviral therapy (HAART) as early as possible, to improve patients's immunity and reduce opportunistic infections. Once considering of clinical PCP, we should treat the patients with SMZ as soon as possible to reduce mortality.关键词
艾滋病/卡氏肺孢子虫肺炎/乳酸脱氢酶/CD4+T细胞引用本文复制引用
彭平,唐小平,胡中伟,邓西龙,郭家伟,童裕维..艾滋病合并卡氏肺孢子虫肺炎107例[J].实用医学杂志,2011,27(4):637-639,3.
