中国组织工程研究与临床康复2011，Vol.15Issue(4)：709-713,5.DOI:10.3969/j.issn.1673-8225.2011.04.034
人工关节无菌性松动的早期诊断
Early diagnosis of artificial joint aseptic loosening
魏慧 1田京1
作者信息
- 1. 南方医科大学附属珠江医院骨科,广东省广州市,510282
- 折叠
摘要
Abstract
BACKGROUND: The most significant factor that affects the life span of joint prosthesis is the artificial joint aseptic loosening.OBJECTIVE: To explore the early diagnosis of artificial joint aseptic loosening methods in order to facilitate active early treatment.METHODS: A computer-based online search of PubMed database, CNKI database, VIP database and Wanfang database between May 1997 and October 2010 was performed to search related articles with the key words of "aseptic loosening, artificial joint, prosthesis, osteolysis, early diagnosis" in English or Chinese. Literatures related to aseptic loosening of prosthesis were selected; in the same field, the articles published lately in authoritative journals were preferred. A total of 182 literatures were primarily selected, and 39 documents of which addressing the analysis and treatment of aseptic loosening of prosthesis were involved for summary according to inclusion criteria.RESULTS AND CONCLUSION: Aseptic loosening of prosthesis and osteolysis has a close relationship with abnormality of bone metabolism and inflammatory reaction. Therefore, related cytokines of inflammatory reaction induced by bone metabolic markers and wear particles can be used for early diagnosis. lsotopic tracer can not only displays the morphology of tissue and organ, but also reflects the function of tissues and organs by showing physiological and biochemical processes of organs or tissues.Pathological changes can be found earlier than imaging for a few weeks or even months.关键词
无菌性松动/人工关节/假体/骨溶解/早期诊断分类
医药卫生引用本文复制引用
魏慧,田京..人工关节无菌性松动的早期诊断[J].中国组织工程研究与临床康复,2011,15(4):709-713,5.
