实用医学杂志2011，Vol.27Issue(4)：577-579,3.DOI:10.3969/j.issn.1006-5725.2011.04.011
RANKL在正常大鼠牙齿及牙周组织中的表达和定量分析
Expression and quantitative analysis of RANKL in normal periodontal tissue of rats
摘要
Abstract
Objective To further understand the expression of receptor activator of NF-kB ligand (RANKL) in teeth and the periodontal tissue and to provide experimental data for the role of RANKL in the preparation of periodontal tissue and hone remodeling. Methods RANKL expression in the normal rat periodontal tissue was analyzed qualitatively and quantitatively using RANKL polyclonal antibody with immunohistochemical staining and the image analysis system. Results RANKL was expressed in the normal periodontal tissue , mainly distrihuting in the cytoplasm of osteohlasts on the surface of alveolar bone, a few of periodontal fibrohlasts , and lymphocytes in gum. The osteocytes showed negative staining. The expression level of RANKL on the distal side was obviously higher than that on the medial side. Conclusions RANKL exists in the normal rat periodontal tissue.The direction of the physiological movement of the rat first molar could be toward the distal side.关键词
转录因子/牙周组织/免疫组织化学染色引用本文复制引用
史瑞新,陈远萍,周延民..RANKL在正常大鼠牙齿及牙周组织中的表达和定量分析[J].实用医学杂志,2011,27(4):577-579,3.基金项目
吉林省科技厅资助项目(编号:200705348) （编号:200705348）
