天然产物研究与开发2011，Vol.23Issue(1)：146-148,197,4.
内蒙古产柽柳和多枝柽柳α-葡萄糖苷酶抑制活性
α-Glucosidase Inhibitory Activity of Tamarix chinensis Lout.and Tamarix ramosissima Ledeb.in Nei Meng-gu
摘要
Abstract
The α-glucosidase inhibitory activities of different extracts from two species Tamarix in Nei Meng-gu were screened and compared with acarbose as positive control in vitro by the 96-microplate-based method for the first time.The results showed that six extracts from two species Tamarix showed good inhibitory activity, and they were all greatly higher than that of acarbose ( IC50 = 1103.0l μg · mL- 1 ) as positive control.Petroleum ether extract had lower inhibitory activity than that of ethyl acetate extract and methanolic extract in the same plant.Extracts from different plant of same polar solvent had different inhibitory activity.In six extracts,the l-butanol extract of T.ramosissima and ethyl acerate extract of T.chinensis had the highest inhibitor activity of α-glucosidase (IC50 = 13.36 和 17.35 μg · mL-1 ).The all extracts of two species Tamarix in Nei Meng-gu had good inhibitory activity of α-glucosidase, and inhibitory activity of T.ranosissima was higher than that of T.chinensis.Two plants could be exploited the diabetes drugs as α-glucosidases inhibitors in future.关键词
柽柳属/柽柳/多枝柽柳/α-葡萄糖苷酶/抑制活性Key words
Tamarix/ T.chinensis/ T.ranosissima/ α-glucosidase/ inhibitory activity分类
医药卫生引用本文复制引用
常星,崔维恒,张俊柯,吴雨虹,康文艺..内蒙古产柽柳和多枝柽柳α-葡萄糖苷酶抑制活性[J].天然产物研究与开发,2011,23(1):146-148,197,4.基金项目
河南大学大学生创新性实验计划(09NB026),河南省教育厅青年骨干教师资助计划(教高[2008]755) （09NB026）
