西安交通大学学报（医学版）2011，Vol.32Issue(2)：261-263,3.
非高密度脂蛋白胆固醇与2型糖尿病的相关性
Correlation between non-high density lipoprotein cholesterol level and type 2 diabetes mellitus
丁丽 1郭炫 1张志峰 2赵珊1
作者信息
- 1. 西安交通大学医学院,第一附属医院检验科,陕西西安,710061
- 2. 西安交通大学医学院,卫生系营养与食品卫生学教研室,陕西西安,710061
- 折叠
摘要
Abstract
Objective To explore the correlation between non-high density lipoprotein cholesterol (non-HDLC) level and type 2 diabetes mellitus (DM). Methods We selected 180 patients with type 2 diabetes as the experimental group and 100 persons who passed the physical check-up served as normal controls. According to complications involving other organs, patients in the experimental group were divided into Grade Ⅰ , Ⅱ and Ⅲ groups. Grade Ⅰ: simple type 2 DM; Grade Ⅱ : type 2 DM with complications involving other organs excluding coronary artery disease (CAD); Grade Ⅲ: type 2 DM complicated with CAD. Total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were measured; non-HDL-C level was calculated. Results Serum non-HDL-C level was significantly higher in DM group than in control group (P ＜ 0.05), and in the experimental group significant differences existed among different sub-groups. Logistic regression analysis showed that in the experimental group OR of serum non-HDL-C was slightly greater than that of TG and obviously stronger than that of TC and LDL-C; OR value had a significant advantage when complications differed. Conclusion Serum non-HDL-C has a positive correlation with different complication development stages of type 2 DM, and the correlation is greater than with TG, TC and LDL-C.关键词
非高密度脂蛋白胆固醇/2型糖尿病/总胆固醇/甘油三酯分类
医药卫生引用本文复制引用
丁丽,郭炫,张志峰,赵珊..非高密度脂蛋白胆固醇与2型糖尿病的相关性[J].西安交通大学学报（医学版）,2011,32(2):261-263,3.
