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检测急性脑梗死患者血小板活化因子的临床意义

尹黎英 李惠媛 张冀平 王璇 刘媛 李建华

武警医学2011,Vol.22Issue(2):129-131,135,4.
武警医学2011,Vol.22Issue(2):129-131,135,4.

检测急性脑梗死患者血小板活化因子的临床意义

Role of platelet activating factor in diagnosis and treatment of acute cerebral infarction

尹黎英 1李惠媛 1张冀平 1王璇 1刘媛 1李建华2

作者信息

  • 1. 030006,太原,武警山西总队医院神经内科
  • 2. 030001,太原市中心医院内科实验室
  • 折叠

摘要

Abstract

Objective To study the relationship between platelet activating factor (PAF) and acute cerebral infarction ( ACI), and the PAF as a target for ACI therapy. Methods PAF levels in plasma were quantified using enzyme - linked immunosorbent assay. Effects of safflower yellow (SY) on nervous function, PAF and hemorheology were tested to further prove the role of PAF in the treatment of ACI. Results The PAF levels in AC1 group were significantly higher than those in healthy control group, and proportional to infarction volume. Improved nervous function and hemorheelogy, decreased PAF levels were observed after SY treatment. Conclusions PAF levels and activity are elevated in ACI patients, and the drug aimed at PAF plays a key role in the treatment of ACI.

关键词

血小板活化因子/急性脑梗死/红花黄色素/神经功能

分类

医药卫生

引用本文复制引用

尹黎英,李惠媛,张冀平,王璇,刘媛,李建华..检测急性脑梗死患者血小板活化因子的临床意义[J].武警医学,2011,22(2):129-131,135,4.

武警医学

OACSTPCD

1004-3594

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