中国组织工程研究与临床康复2011,Vol.15Issue(5):851-854,4.DOI:10.3969/j.issn.1673-8225.2011.05.022
脱细胞猪皮为覆盖物的微粒皮移植修复大面积深度烧伤创面
Acellular porcine skin to cover auto-microskin graft for repair of extensive deep burns
田诗政 1杨萍 1王鹏 1陆华 1张赛圣 1杨志宏1
作者信息
- 1. 湖北医药学院附属人民医院烧伤整形科,湖北省十堰市,442000
- 折叠
摘要
Abstract
BACKGROUND:Besides allogeneic skin, porcine skin, buckskin, autoallergic eschar, or vaseline gauze are used as microskin coverings, especially the porcine skin, which is extensive used due to similar to human skin structures and low costs.OBJECTIVE:To observe the clinical effects of acellular porcine skin to cover auto-microskin on extensive deep burns.METHODS:Fifteen cases with extensive deep burns were treated with removal of eschar at the early stage or granulation tissue debridement, transplantation of auto-microskin covered with acellular porcine skin . The rejection of acellular porcine skin, the survival of the microskin grafts and wound repair of skin were observed and retrospectively analyzed postoperatively.RESULTS AND CONCLUSION:The acellular porcine skin could suck intact in the wound postoperatively. And it turned to cinnamomeous or purple black and a dry scab within 5-7 post-operation days, a small amount of exudate was found under covering occasionally, and the acellular porcine skin did not become soft and was not stripped after fenestration and drainage.The porcine skin gradually separated from the auto-microskin during 3-4 weeks post-operation. The wound completely healed,and the appearance and elasticity of skin recovered to some extent, and scars were inconspicuous. The results showed that it is reliable to use acellular porcine skin as a substitute of alloskin to cover auto-microskin in the treatment of extensive deep burns, and the wound is ideally repaired.关键词
脱细胞猪皮/自体微粒皮/移植/烧伤/创面分类
医药卫生引用本文复制引用
田诗政,杨萍,王鹏,陆华,张赛圣,杨志宏..脱细胞猪皮为覆盖物的微粒皮移植修复大面积深度烧伤创面[J].中国组织工程研究与临床康复,2011,15(5):851-854,4.