西安交通大学学报（医学版）2011，Vol.32Issue(2)：190-192,3.
蒜氨酸、蒜酶及二者联用对耐甲氧西林金黄色葡萄球菌的抗菌作用
In vitro antibacterial effects of alliin, alliinase and alliin+alliinase against methicillin-resistant Staphylococcus aureus
陈锋 1朱震宏 2刘素辉 1顾丹今 1陈坚 3孙玉萍1
作者信息
- 1. 新疆医科大学,基础医学院,新疆乌鲁木齐,830054
- 2. 新疆医科大学,第一附属医院检验科,新疆乌鲁木齐,830054
- 3. 新疆医科大学,药学院,新疆乌鲁木齐,830054
- 折叠
摘要
Abstract
Objective To investigate in vitro antibacterial effects of alliin, alliinase and alliin + alliinase against methicillin-resistant Staphylococcus aureus (MRSA).Methods Broth dilution and agar count methods were used to determine in vitro antibacterial effects of alliin, alliinase and alliin + alliinase against 10 clinically isolated MRSA strains.Time killing curves were drawn.Results Alliin and alliin+ alliinase showed antimicrobial activities against MRSA, but alliinase could not inhibit their growth.Conclusion Both alliin and alliin + alliinase are antimicrobial drugs sensitive to MRSA and thus have the prospect of treating infectious diseases caused by MRSA.关键词
蒜氨酸/蒜酶/耐甲氧西林金黄色葡萄球菌/最小抑菌浓度/最小杀菌浓度/时间-杀伤曲线分类
医药卫生引用本文复制引用
陈锋,朱震宏,刘素辉,顾丹今,陈坚,孙玉萍..蒜氨酸、蒜酶及二者联用对耐甲氧西林金黄色葡萄球菌的抗菌作用[J].西安交通大学学报（医学版）,2011,32(2):190-192,3.
