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外源性神经生长因子对外周神经侧枝发芽GAP-43表达的调控

李旭东 刘刚 赵烨德

中国美容医学2011,Vol.20Issue(2):255-256,2.
中国美容医学2011,Vol.20Issue(2):255-256,2.

外源性神经生长因子对外周神经侧枝发芽GAP-43表达的调控

Expression of nerve growth factor in lateral sprouting after peripheral nerve end-to-side anastomosis

李旭东 1刘刚 1赵烨德1

作者信息

  • 1. 解放军第411医院整形外科,上海,200081
  • 折叠

摘要

Abstract

Objective To explore the expression of nerve growth factor in lateral sprouting after peripheral nerve end-to-side anastomosis and find the mechanism of lateral sprouting. Methods 32 SD rats were randomly divided into four groups: 1 week group, 2 week group, 4 week group and 8 week group. Immunohistochemical analysis by the computer image analysis was performed to study the expression of the NGF after end-to-side anastomosis. Results Increased expression of NGF were observed in distal ends after end-to-side anastomosis, and on more expression of NGF in proximal ends was also observed. Conclusion It show that the nerve growth factors in distal ends may be acts as an important role in lateral sprouting.

关键词

神经再生/端侧吻合/侧支发芽/神经生长因子/GAP-43

分类

医药卫生

引用本文复制引用

李旭东,刘刚,赵烨德..外源性神经生长因子对外周神经侧枝发芽GAP-43表达的调控[J].中国美容医学,2011,20(2):255-256,2.

中国美容医学

1008-6455

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