中国医学科学院学报2011，Vol.33Issue(1)：83-87,5.DOI:10.3881/j.issn.1000-503X.2011.01.018
不明原因发热的病因分布及临床特征
Etiology and Clinical Features of Fever of Unknown Origin
马锦玲 1曹剑 1王玉堂 1郭园园 1孟庆义2
作者信息
- 1. 中国人民解放军总院南楼心血管一科,北京100853
- 2. 中国人民解放军总院急诊科,北京100853
- 折叠
摘要
Abstract
Objective To investigate the etiology and clinical features of fever of unknown origin (FUO). Methods The clinical data including etiology, diagnostic approaches, and clinical features were retrospeetively analyzed in 816 patients with FUO who were presented in our department from January 2000 to January 2009. Results Of these 816 FUO eases, 766 (93.9％) were confirmed to be with infective diseases (40.4％, n=330), connective tissue diseases (34.4％, n=281 ), malignant tumors ( 10.9％, n=89),other known diseases (8.1％, n=66), and unknown diseases (6.1％, n=50). The most common infective disease was tuberculosis (49.7 ％ , 164/330) , the most common connective tissue disease was adult-onset Still's disease (AOSD) (55.2％ , 155/281 ) , the most common malignant tumor was lymphoma (56.2％ ,50/89) , and the most common "other known disease" was Crohn's disease (22.7％ , 15/66). All lung caneer eases had obstructive pneumonia. Significantly more elderly patients suffered from infective diseases (49.4％ vs. 32.0％ ) and malignant tumor ( 15.6％ vs. 6.4％ ) compared with the non-elderly ( both P=0. 0000), while the proportion of connective tissue diseases was significantly less than that of the non-elderly (17.9％ vs. 50. 1％ , P=0. 0000). Conclusions Most FUO can be confirmed after careful examinations and analysis. The main cause of FUO is infective diseases, especially tuberculosis in the elderly. The eonnective tissue diseases and malignant tumors are also important causes.关键词
不明原因发热/病因分布/临床特征分类
医药卫生引用本文复制引用
马锦玲,曹剑,王玉堂,郭园园,孟庆义..不明原因发热的病因分布及临床特征 [J].中国医学科学院学报,2011,33(1):83-87,5.
