南方医科大学学报2011，Vol.31Issue(2)：377-379,3.
经后穹窿穿刺盆腔注射甲氨蝶呤治疗输卵管妊娠的临床研究
Therapeutic effect of pelvic methotrexate injection via the posterior fornix for treatment of tubal pregnancy
杨秀丽 1曹玉平 1刘志辉1
作者信息
- 1. 东莞市常平医院妇产科,广东,东莞,523560
- 折叠
摘要
Abstract
Objective To evaluate the therapeutic effect and safety of pelvic methotrexate (MTX) injection via the posterior fornix for treatment of tubal pregnancy. Methods Ninety-six patients with tubal pregnancy (mean age 21-40 years) were randomized into 3 groups for treatment with pelvic MTX injection via the posterior fornix+mifepristone+ traditional Chinese medicine (experiment group), intramuscular MTX injection + mifepristone + traditional Chinese medicine (control group I), or mifepristone+traditional Chinese medicine (control group Ⅱ). On days 4 and 7 of the treatment, blood β-HCG of the patients in different groups was detected, and in cases with continuous reduction of blood β-HCG or a reduction by over 15%,β-HCG was checked every week. One week after the treatment, the size of the mass was measured by B-mode ultrasound. The clearance time of β-HCG and the hospital stay of the patients were recorded. Results Twenty-nine patients in the experimental group were treated successfully, with a cure rate of 90.6%, which was significantly higher than those in the two control groups (P<0.05). The clearance time of β-HCG and hospital stay were also much shorter in the experimental group (P＜0.05). Conclusion Pelvic MTX injection via the posterior fomix is a convenient procedure associated with minimal complications and serves as a good alternative for treatment of tubal pregnancy.关键词
甲氨蝶呤/米非司酮/输卵管妊娠/后穹窿/β-人绒毛膜促性腺激素Key words
methotrexate/ mifepristone/ tubal pregnancy/ posterior fornix/ chorionic gonadotropin, beta subunit, human分类
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杨秀丽,曹玉平,刘志辉..经后穹窿穿刺盆腔注射甲氨蝶呤治疗输卵管妊娠的临床研究[J].南方医科大学学报,2011,31(2):377-379,3.
