中国实用儿科杂志2011，Vol.26Issue(2)：97-100,4.
不同血流动力学类型血管迷走性晕厥63例预后研究
Follow-up study of the efficacy of different therapies on vasovagal syncope in children with different hemodynamic patterns
摘要
Abstract
Objective To explore the individualized treatment for vasovagal syncope (VVS) in children with different hemodynamic patterns.Methods A total of 63 children aged 6 ～ 19 years [mean age (11.57 ± 2.89) years]with VVS were followed up in clinics or by telephone.Totally 32 cases were diagnosed as VVS vasodepressor type, 31 cases were diagnosed as VVS mixed type or cardioinhibitory type.Fourteen cases took oral rehydration salts, 13 cases took metoprolol and 36 cases took midodrine hydrochloride as initial treatment.Patients were followed up for 3 ～ 48 months,with a mean of (21 ± 12) months.The recurrence of syncope in 3 months was studied to evaluate short-term efficacy of 3 different therapies.Taking recurrence of syncope as events, Kaplan-Meier curves were drawn to compare long-term efficacy of different therapies in treating VVS children.Results There was no statistical difference for the short-term efficacy among the diffrent hemodynemic patterns when treated with oral rehydration salts, or metoprolol or midodrine hydrochloride (oral rehydration: x2 = 0.498, P ＞ 0.05; metoprol: x 2 = 0.627, P ＞ 0.05; midodrine hydrochloride: x 2 = 2.057, P ＞ 0.05).There was no statistical difference for the long-term efficacy among VVS children with different hemodynamic patterns when treated with oral rehydration salts, or metoprolol.Patients with mixed or cardioin hibitory patterns had a better response than those with vasodepressor pattern to midodrine hydrochloride (P ＜ 0.01) Conclusions Oral rehydration salts, metoprolol or midodrine hydrochloride are appropriate to treat children with VVS.Children with VVS mixed and cardioinhibitory patterns are more appropriate to take midodrine hydrochloride as initial treatment.关键词
晕厥,血管迷走神经性/口服补液盐/美托洛尔/盐酸米多君/儿童分类
医药卫生引用本文复制引用
张凤文,廖莹,李雪迎,陈丽,金红芳,杜军保..不同血流动力学类型血管迷走性晕厥63例预后研究[J].中国实用儿科杂志,2011,26(2):97-100,4.基金项目
首都医学发展科研基金(2007-2003),北京市科技计划(D10100050010059) （2007-2003）
