摘要
Abstract
Objective To discuss the relation between early manifestations and severity of chemotherapy-related infection in children with tumor. Methods The manifestations of infection during or after chemotherapy in 346 cases of 136 children with tumor were analyzed, and the differences in early manifestations between severe and mild infection were compared. Results One hundred and thirty-three cases had severe infection, and 213 cases had mild infection. The incidences of chill, ague, fatigue, poor peripheral circulation and neutropenia in severe infection were significantly higher than those in mild infection. The highest temperature and the level of CRP at 6 to 12 hours during fever in severe infection were significantly higher than those in mild infection; on the other hand, the probability to be severe infection in children with intensive chemotherapy, chill, ague, fatigue, poor peripheral circulation, absolute neutrophil count (ANC) ≤0.5 ×109/L, CRP ≥ 40 mg/L, temperature ≥ 39.5 ℃ was higher than that in those without these manifestations (P ＜ 0.05).Conclusions Children with intensive chemotherapy, chill, ague, fatigue, poor peripheral circulation, absolute neutrophil count (ANC) ≤ 0.5 × 109/L,CRP ≥ 40 mg/L,temperature ≥ 39.5 ℃ are more frequently to have severe infection.关键词
感染/肿瘤/儿童/重症感染分类
医药卫生
