中国医学科学院学报2011，Vol.33Issue(1)：66-70,5.DOI:10.3881/j.issn.1000-503X.2011.01.014
基于磁共振分区的健康膝关节软骨T2图
T2 Mapping of Articular Cartilage in the Healthy Knee Using A Magnetic Resonance Segmentation
胡娜 1张燕 2盛敏 2吴志宏 2孟薇 3徐进 2姜波 2刘东 2金征宇2
作者信息
- 1. 四川大学华西医院放射科,成都,610041
- 2. 中国医学科学院,北京协和医学院,北京协和医院放射科,北京,100730
- 3. 中国医学科学院,北京协和医学院,北京协和医院骨科,北京,100730
- 折叠
摘要
Abstract
Objective To evaluate T2 mapping of the healthy knee articular cartilage in different subregions using a magnetic resonance segmentation.Methods T2 mapping was performed to 77 healthy tibiofemoral cartilages, which were divided into group H1 ( ＜ 40 years old) and group H2 ( ≥40 years old).T2 values of cartilage in 10 subregions based on the Whole-Organ Magnetic Resonance Imaging Score (WORMS) segmentation and body mass index (BMI) were calculated.T2 values of cartilage in 10 subregions were compared.The association between T2 value and BMI/age was analyzed.The intra- and inter-observer reproducibility of measurement was calculated.Results The T2 values of all the subregions ranged 40.3-53.5 ms.T2 values of group H2 were significantly higher than those in group H1 ( P ≤ 0.032 ) except in posterior lateral femoral subregion.The inter-subregion differences within group were significant ( P ＜ 0.001 ).The inter-gender differences were significant only in posterior medial tibial subregion of group H2 (P= 0.048 ).No correlation of T2 values with BMI was found except in cetral lateral tibial subregion of group H2 (P= 0.050, R= 0.308 ).T2 values were correlated with age in anterior medial (P= 0.004, R= -0.467 ) and anterior lateral ( P =0.024, R = -0.375 ) tibial subregions of group H1, and in all tibial subregions except anterior lateral tibial subregion of group H2, and central medial femoral subregion of group H2 (P=0.004 ～0.015, R =0.376 ～ 0.437).The correlation coefficients for intra- and inter-observer of measurement showed good reproducibility (R ＞ 0.809, P ≤ 0.005 ).Conclusion T2 mapping of the healthy knee articular cartilage based on the WORMS segmentation can effectively reflect the changes and correlations of T2 values with risk factors by focusing on the functional weight-bearing subregions.关键词
骨关节炎/关节软骨/磁共振成像/T2图/全器官磁共振成像评分分类
医药卫生引用本文复制引用
胡娜,张燕,盛敏,吴志宏,孟薇,徐进,姜波,刘东,金征宇..基于磁共振分区的健康膝关节软骨T2图 [J].中国医学科学院学报,2011,33(1):66-70,5.
