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尿液表面增强拉曼光谱的初步研究

陈杰斯 冯尚源 林居强 俞允 邱文强 伍严安 潘建基 陈荣

激光生物学报2011,Vol.20Issue(1):98-102,5.
激光生物学报2011,Vol.20Issue(1):98-102,5.DOI:10.3969/j.issn.1007-7146.2011.01.019

尿液表面增强拉曼光谱的初步研究

The Preliminary Study of Urine by Surface Enhanced Raman Spectroscopy

陈杰斯 1冯尚源 1林居强 1俞允 1邱文强 1伍严安 2潘建基 3陈荣1

作者信息

  • 1. 医学光电科学与技术教育部重点实验室,福建师范大学,福建,福州,350007
  • 2. 福建省立医院,福建,福州,350001
  • 3. 福建省肿瘤医院,福建,福州,350014
  • 折叠

摘要

Abstract

The absorption spectroscopy of silver colloids and the mixture of silver colloids with urine were measured.The urine' s Raman spectroscopy were tested and analyzed before and after the adding of silver colloids.Based on the technology of Surface Enhanced Raman Spectroscopy, the intensity of the urine' s Raman signal in the silver colloids was increased obviously and the SERS signal of uric acid in urine was successfully detected.The characteristic Raman bands of urine were tentatively assigned.The SERS of the urine of the morning and the night were compared and analyzed.The detection of morning urine bears higher credibility and SNR.The results showed that the surface-enhanced Raman spectroscopy might provide a new kind of method for the clinic detection of urine.

关键词

表面增强拉曼光谱/检测/尿液/银溶胶

Key words

Surface Enhanced Raman Spectroscopy/ detecting/ urine/ silver colloidal

分类

生物科学

引用本文复制引用

陈杰斯,冯尚源,林居强,俞允,邱文强,伍严安,潘建基,陈荣..尿液表面增强拉曼光谱的初步研究[J].激光生物学报,2011,20(1):98-102,5.

基金项目

国家自然科学基金(60778046,60910106016) (60778046,60910106016)

福建省科技项目(200810015,2008J0016) (200810015,2008J0016)

卫生部科研基金(WKJ2008-2-046) (WKJ2008-2-046)

激光生物学报

OACSCDCSTPCD

1007-7146

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