激光生物学报2011，Vol.20Issue(1)：125-129,5.DOI:10.3969/j.issn.1007-7146.2011.01.024
靶向纳米探针介导的近红外激光热疗
Near-infrared Region Photothermal Therapy using Targeting Nanoprobe
摘要
Abstract
The pursuit of efficient and highly target-selective transporters is an active topic in cancer targeting therapy.Here, a novel functioned nanoprobe based on integrin αvβ3 monoclonal antibody labeled carbon nanotubes was developed to targeting and killing cancer cells under laser irradiation. The results revealed that the nanoprobe had a high efficieney in cancer cell targeting and killing in integrin αvβ3 positive U87MG cells, could be used as a potential photothermal transduction nanoprobe for cancer targeting therapy.关键词
肿瘤靶向治疗/碳纳米管/光热治疗/靶向探针Key words
cancer targeting therapy/ carbon nanotubes/ photothermal therapy/ targeting probe分类
医药卫生引用本文复制引用
周非凡,宋盛,吴宝艳,欧忠敏,邢达..靶向纳米探针介导的近红外激光热疗[J].激光生物学报,2011,20(1):125-129,5.基金项目
科技部国家重点基础研究973计划项目(2010CB732602 （）
2011CB910402) （）
教育部"长江学者与创新团队计划"创新团队项目(IRT0829)和国家自然科学基金项目(30870676 （IRT0829）
30870658 （）
30800261) （）
