北京中医药大学学报2011，Vol.34Issue(2)：122-125,4.
远志化学成分分离与结构鉴定
Isolation and structure identification of chemical constituent of Yuanzhi ( Radix Polygalae)
摘要
Abstract
Objective To study the chemical constituents of Yuanzhi ( Radix Polygalae) and to expound the material foundation of Yuanzhi's medicinal action. Methods The chemical constituents of Yuanzhi were extracted with ethanol extractive method, and isolated and purified with various column chromatographic and crystallization methods including silica gel, ODS, gelatum, polyamide and MCI.The structures of the isolated compounds were identified by using different spectroscopic and chromatographic techniques including UV, IR, MS and NMR. Results There were 12 compounds isolated and identified from Yuanzhi, including fal-laxsaponin A ( 1 ), temiifolin ( 2 ), αt-D-( 6-O-sinopoyol)-glucopyyranosyl ( 1 → 2 )-β-D-( 3-O-sinapoyl )-fructofuranose ( 3 ), sibricose A6 ( 4 ), tenuifoliside B (5), tenuifoliside C (6), sibricose A2 (7), polygalaxanthone Ⅳ ( 8 ), 3,4,5-trimethoxy cinnamate ( 9 ), 4-hydroxy-3,5-dimethoxylcinnamate ( 10 ), 3,4, 5-trimethoxycinnamate ( 11 ), and 2-hydroxylbenzonic acid(12). Conclusion The compounds 1,11 and 12 were isolated from Yuanzhi for the first time.关键词
远志/皂苷/寡糖酯/酮Key words
Yuanzhi (Radix Polygalae)/ saponin/ sucrose ester/ xanthones分类
医药卫生引用本文复制引用
姜艳艳,段以以,刘洋,方敏,石任兵..远志化学成分分离与结构鉴定[J].北京中医药大学学报,2011,34(2):122-125,4.基金项目
国家重大新药创新资助项目(No.2009ZX09502-006),国家"211"工程建设资助项目 （No.2009ZX09502-006）
