山东医药2011，Vol.51Issue(7)：15-17,3.
十全大补汤总多糖的体外抗肿瘤作用
Anti-tumor effects of total polysaccharide extracted from Shiquan Dabu Decoction in vitro
摘要
Abstract
Objective To investigate the anti-tumor effects of total polysaccharide (TPS) extracted from Shiquan Dabu Decoction in vitro, so as to provide basis for its clinical application and research of anti-tumor drugs.Methods The human lung cancer cells A549, hepatoma cells Bel-7402, colorectal carcinoma cells HCT-8 and cervical carcinoma cells Hela cultured in vitro were treated with TPS of 200,100, 50 μg,/ml, the inhibitory rate of proliferation were measured by MTT assay at 24,48,72 h after the treatment.Results IR reached the highest in the A549 cells when treated with TPS of 200 μg/ml for 48 hs; IR in the other three kinds of cells increased gradually with the increasing of TPS concentration and prolonging of treating time, reached the highest at 200 μg/ml for 72 hs, which showed dose and time-dependent manner.Conclusions TPS could inhibit the growth of tumor in vitro; and hope to be used for the treatment of tumor as anti-tumor drugs.关键词
十全大补汤,总多糖/肿瘤细胞,增殖抑制分类
医药卫生引用本文复制引用
戎瑞雪,王蓓,曹志然,唐志远,赵丽君,王晓晖..十全大补汤总多糖的体外抗肿瘤作用[J].山东医药,2011,51(7):15-17,3.基金项目
河北大学医学部科学研究基金项目(2007Y06). （2007Y06）
