同济大学学报（医学版）2011，Vol.32Issue(1)：61-64,4.DOI:10.3969/j.issn1008-0392.2011.01.061
不同药物体外受精-胚胎移植的黄体支持比较
Comparison of different routs of progesterone administation as luteal phase support in vitro fertilization
张韶珍 1吴青 1冯云1
作者信息
- 1. 上海交通大学医学院附属瑞金医院生殖医学中心,上海,200025
- 折叠
摘要
Abstract
Objective To study the effects of different luteal supplementation on in vitro fertilization,frozen embryo transter(FET) and early pregnancy complicated by threatened abortion.Methods Embryo score, bleeding, ongonging pregnant rate and early abortion rate were analyzed retrospectively.IVF cycles were divided into group A progesterone + vaginal progesterone caps, increasing injection dose 60 ～80 mg to stop vaginal IVF cycles and group B progesterone + Dydrogesterone,using Dydrogesterone 10 mg every 8 hrs to stop vaginal bleeding.Frozen embryo transter cycles were divided into group C progesterone, increasing injection dose 60 ～80 mg to stop vaginal bleeding and group D progesterone,using Dydrogesterone 40mg followed with 10mg every 8 hrs for vaginal bleeding.Results IVF cycle's bleeding and abortion rate of early pregnancy were lower statistically than that of FET cycle.The bleeding rate was higher and the ongonging pregnant rate was lower in the IVF group using vaginal progesterone caps than those in Dydrogesterone group.But the differences were not significant.The ongonging pregnant rate of the group using Dydrogesterone for vaginal bleeding was higher than the one using progesterone injection,but their differences were not significant.Conclusion The effects of luteal supplementation are similar using progesterone caps and Dydrogesterone.The results of using progesterone injection or dydrogesterone to stop vaginal bleeding are similar with dydrogesterone having a little superiority.The selection of medicine should be made by patiens' specific status.Personalized medicine may be more suitable for clinical application.关键词
体外受精-胚胎移植/黄体支持/止血分类
医药卫生引用本文复制引用
张韶珍,吴青,冯云..不同药物体外受精-胚胎移植的黄体支持比较[J].同济大学学报（医学版）,2011,32(1):61-64,4.
