中国全科医学2011，Vol.14Issue(5)：566-568,3.
万古霉素致移植肾急性肾小管坏死一例分析
Vancomycin-associated Acute Kidney Tubular Necrosis in Renal Allograft:Report of One Case
谭庆 1孙煦勇 1聂峰 1杨建均 1赖彦华 1董建辉 1曹嵩 1黄莹1
作者信息
- 1. 530021,广西壮族自治区南宁市,中国人民解放军第三零三医院移植医学研究院
- 折叠
摘要
Abstract
A 49 - year- old men was admitted due to 5 - hour fever. He underwent kidney transplantation 6 month ago. He was diagnozed as infection in both two lungs upon admission examinations. Initial treatment with anti - infection drugs showed poor results. Vancomycin was then applied based on the lung lavage and drug - sensitivity test results. After 3 days of treatment with vancomycin, the symptoms were somehow relieved, but accompanied by less urine and higher blood pressure. It was preliminarily considered as acute rejection, and methyl prednisolone acetate was applied. However, the volume of urine did not increase. Biopsy of the kidney graft showed acute kidney tubular necrosis and acute allergic tubulointerstitial nephritis, which were believed to be drug-associated. Vancomycin was stopped, and linezolid and haemodialysis were applied. Fourteen days later, the volume of urine gradually increased and the renal function returned normal, and the patient was discharged.关键词
肾移植/万古霉素/肾小球分类
医药卫生引用本文复制引用
谭庆,孙煦勇,聂峰,杨建均,赖彦华,董建辉,曹嵩,黄莹..万古霉素致移植肾急性肾小管坏死一例分析[J].中国全科医学,2011,14(5):566-568,3.
