中国全科医学2011，Vol.14Issue(5)：545-547,3.
131Ⅰ治疗199例Graves病近期疗效观察
The Short-term Therapeutic Effect of 131 Ⅰ in the Treatment of 199 Patients with Graves Disease
刘海春 1陈阳 1李东伟 1郑宇1
作者信息
- 1. 102413北京市,中国核工业北京四〇一医院核医学科
- 折叠
摘要
Abstract
Objective To discuss the short - term efficacy of individual 131Ⅰ dose treatment for the Graves disease. Methods 199 patients with Graves disease were given individual I dose treatment ( between 1. 60 to 6. 90 MBq/g ) for the first time. They were then followed for 12 months, recording their symptoms, signs, serum thyroid hormones and autoantibody, blood and so on. Results After 12 months, 199 Graves disease patients who were given individual 131Ⅰ -dose treatment for the first time, 131 cases were cured ( 65. 8％ ), 34 cases improved ( 17. 1％ ), 29 cases hypothyroidism ( referred to as a low ) ( 14. 6％ ), 5 cases ineffective ( 2. 5％ ). There were no significant differences in the cured rate ( 72. 5％ , 63. 2％ , and 60. 5％ ) and hypothyroidism rate ( 17. 4％ , 17. 2％ , and 4. 7％ ) between patients with different thyroid gland weight ( P ＞ 0. 05 ). Conclusion I therapy is a safe, simple and the effective method for Graves disease, and no significant difference was shown in therapeutic effect between patients with different thyroid gland weight.关键词
甲状腺功能亢进症/碘放射性同位素/治疗结果分类
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刘海春,陈阳,李东伟,郑宇..131Ⅰ治疗199例Graves病近期疗效观察[J].中国全科医学,2011,14(5):545-547,3.
