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超声量化指标对慢性肝炎肝纤维化的诊断价值研究

徐桂娟 杨晴 刘东屏 陈阳

中国全科医学2011,Vol.14Issue(6):687-689,3.
中国全科医学2011,Vol.14Issue(6):687-689,3.

超声量化指标对慢性肝炎肝纤维化的诊断价值研究

Evaluation of the Value of Ultrasonography in the Diagnosis of Liver Fibrosis in Chronic Hepatitis B Patients

徐桂娟 1杨晴 1刘东屏 2陈阳1

作者信息

  • 1. 110006,辽宁省沈阳市第六人民医院
  • 2. 中国医科大学第一临床学院消化内科
  • 折叠

摘要

Abstract

Objective To discuss the diagnostic value of ultrasonography ( US ) for detecting the severity of hepatic fibrosis in chronic hepatitis B patients. Methods 448 chronic hepatitis B patients were evaluated by US. The results of US were compared with the results of pathological diagnosis to determine the most valuable factor for diagnosing hepatic fibrosis in chronic hepatitis B patients. Results The spleen length ( SPL ), gall-bladder wall thickness, spleen thickness ( SPT ), internal diameter of portal vein and the internal diameter of splenic vein showed a positive correlation with liver fibrosis level ( P<0. 01 ), spearman correlation coefficient ( r) were 0.501, 0.496, 0.491, 0.334 and 0. 160 respectively, and all these parameters showed statistics differences among patients with different hepatic fibrosis levels ( P <0. 05 ). SPL and SPT had important significance in diagnosing patients in ≥S2 stages especially in > S3 [ Area under receiver operating characteristic curve ( AUROC ) were 0. 751 and 0. 757, 0. 794 and 0. 786 ] while gall - bladder wall thickness had important significance in diagnosing patients in ≥S3 stages ( AUROC were 0. 804 ). Conclusion SPL, SPT and gall-bladder wall thickness are valuable parameters for the diagnosis of hepatic fibrosis, and it is applicable to follow-up survey.

关键词

肝硬化/超声检查/诊断

分类

医药卫生

引用本文复制引用

徐桂娟,杨晴,刘东屏,陈阳..超声量化指标对慢性肝炎肝纤维化的诊断价值研究[J].中国全科医学,2011,14(6):687-689,3.

中国全科医学

OA北大核心CSTPCD

1007-9572

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