中国临床保健杂志2011，Vol.14Issue(1)：34-37,4.DOI:10.3969/J.issn.1672-6790.2011.01.012
高血压患者高敏C-反应蛋白及脂联素与颈动脉粥样硬化的相关性研究
Correlation of C-reactive protein and adiponectin to carotidarte ry atherosclerosis in hypertensive patients
张玉英 1韩增雷 2王津文2
作者信息
- 1. 山东青岛市城阳区第三人民医院,266107
- 2. 青岛市第八人民医院心内科
- 折叠
摘要
Abstract
Objective To study the correlation of carotid atherosclerosis with C-reactive protein and adiponectin in hypertensive patients.Methods According to bilateral carotid artery echocardiography,226 hypertensive patients were divided into no carotid artery plaque group ( CA-1 group, n = 94 ) and carotid artery plaque group ( CA-2 group,n = 132)to 36 healthy normal contrul group.Serum insulin, high sensitivity C-reactive protein and adiponectin were tested and semi-quantitative estimates of the extent and severity of plaque of carotidartery were evaluated by ultrasonography.Results 1.Intima-media thickness(IMT) ,insulin resistance index ( HOMA-IR), high sensitive C-reactive protein( hs-CRP) in CA-1 group and CA-2 group were significantly higher than those in control group(P ＜ 0.01 ) ,adiponectin was significantly lower than that in control group( P ＜0.01 ).There were significant difference in indexes above between CA-1 group and CA-2 group( P＜0.01 ).2.IMT was positively correlated with HOMA-IR and hs-CRP( P ＜ 0.01 ), while negatively correlated with Adiponectin ( P ＜ 0.01 ).Conclusion C-reactive protein, adiponectin and insulin resistance in hypertensive patients is correlated with carotid atherosclerosis.关键词
高血压/C反应蛋白质/脂联素/动脉粥样硬化/胰岛素抵抗Key words
Hypertension/ C-reactive protein/ Adiponectin/ Atherosclerosis/ Insulin resistance分类
医药卫生引用本文复制引用
张玉英,韩增雷,王津文..高血压患者高敏C-反应蛋白及脂联素与颈动脉粥样硬化的相关性研究[J].中国临床保健杂志,2011,14(1):34-37,4.
