重庆医学2011，Vol.40Issue(7)：663-665,3.DOI:10.3969/j.issn.1671-8348.2011.07.015
联合超滤减轻体外循环对低体质量婴儿心脏手术后的肺损伤
Combined ultrafiltration can attenuate lung injury duing cardiopulmonary bypass after cardioac operation in low weight infants
胡卫 1马瑞彦 1刘梅 1彭莉 1杨宗英 1肖娟 1肖颖彬 1陈林 1王学峰 1郝嘉 1陈劲进 1陈柏成 1王咏 1程伟1
作者信息
- 1. 第三军医大学附属新桥医院心血管外科,重庆,400037
- 折叠
摘要
Abstract
Objective To compare the effects of combined ultrafiltration and conventional ultrafiltration in protecting patients＇pulmonary function duing cardiopulmonary bypass of infants. Methods Forty infantile cardiac surgery patients(weight less than 6 kg)were divided into two groups:combined ultrafiltration group(n = 20)and conventional ultrafiltration group(n = 20). Combined ultrafiltration group did zero balanced ultrafiltration, conventional ultrafiltration and modified ultrafiltration in turn. Conventional group only did conventional ultrafiltration. The volume of ultrafiltration, hematocrit(HCT), concentration of serum album before/ after ultrafiltration were observed. The pulmonary function parameters after the operation, such as oxygenation index, alveolar-arte rial oxygen difference(A-aDO2), static lung compliance, ventilator time and ICU stay time, were respectively monitored. Results Comparing with the conventional group, the blood volume needed in the operation was significantly less, HCT and concentration of serum album in after operration were significantly much increased in the combined ultrafiltration group. The improvement of lung ventilation and gas exchange in the combined ultrafiltration group were significantly obvious than that in the conventional group. In the combined ultrafiltration group, the count of white blood cell, neutrophilic granulocyte after operation and other inflammatory mediators were significantly lower than those in conventional ultrafiltration. For the combined ultrafiltration group, the improvement of lung function was more obvious,especially to the low age and weight infants. Conclusion Combined ultrafiltration has more effictive in protecting patients＇ pulmonary function duing cardiopulmonary bypass of infants compared with conventional ultrafiltration, especially to the low age and weight infant.关键词
体外循环/超滤/呼吸功能试验Key words
extracorporeal circulation/ ultrafiltration/ respiratory function tests引用本文复制引用
胡卫,马瑞彦,刘梅,彭莉,杨宗英,肖娟,肖颖彬,陈林,王学峰,郝嘉,陈劲进,陈柏成,王咏,程伟..联合超滤减轻体外循环对低体质量婴儿心脏手术后的肺损伤[J].重庆医学,2011,40(7):663-665,3.
