肿瘤预防与治疗2011，Vol.24Issue(1)：14-17,4.DOI:10.3969/j.issn.1674-0904.2011.01.004
鼻咽癌调强放疗过程中进行计划调整后的剂量分析
A Study of Replanning during the Course of IMRT for Nasopharyngeal Carcinoma
摘要
Abstract
Objective: We conducted this retrospective study to determine the dosimetric effects of replanning during the course of intensity-modulated radiotherapy ( IMRT ) on hoth normal tissues and target volumes. Methods : A retrospective chart review identified 15 patients with nasopharyngeal carcinoma treated with IMRT, who had replanning during the course of radiotherapy. The first IMRT plan for each patient was generated based on the original CT imaging acquired before the start of treatment. , the second plan was generated after 20 ～ 22 fractions and used to complete the course of IMRT. By using a CORVUS6. 2 planning system, a hyhrid IMRT plan was generated for each patient by copy the first IMRT plan to the anatomy of the second imaging. Results : The hybrid IMRTplans demonstrated reduced the percent of volume receiving 95％ of the prescrihed dose ( V95％ ) of target volumes and increased doses to normal tissues. Conclusion: The target volume dose and normal tissue dose may undergo obvious changes during the course of radiotherapy. Acquire replanning during the course of IMRT for selected patients with nasopharyngeal carcinoma is essential and worth encouraging to identify dosimetric changes and to ensure adequate doses to target volumes and safe doses to normal tissues, especially to the patients whose target volumes shrink and other anatomical variations significantly.关键词
鼻咽癌/调强放射治疗/计划调整分类
医药卫生引用本文复制引用
彭倩,黎杰,冯梅,肖明勇,郎锦义..鼻咽癌调强放疗过程中进行计划调整后的剂量分析[J].肿瘤预防与治疗,2011,24(1):14-17,4.基金项目
四川省科技厅重点科研课题(05SG022-013) （05SG022-013）
