中国实用外科杂志2011，Vol.31Issue(2)：147-149,3.
食管胃结合部腺癌病人行近端与全胃切除术后生活质量比较
Comparison of quality of life between proximal versus total gastrectomy for adenocarcinoma of gastroesophageal junction
代斌 1陈佳平 1潘琳 2杨晨 2刘杰 1陈心足 1杨昆 1胡建昆 1张波 1陈志新1
作者信息
- 1. 四川大学华西医院胃肠外科中心,四川成都,610041
- 2. 四川大学华西临床医学院临床医学系,四川成都,610041
- 折叠
摘要
Abstract
Objective To compare quality of life (QLQ) after proximal gastrectomy (PG) or total gastrectomy (TG) for adenocarcinoma of gastroesophageal junction (AEG) (Siewert type Ⅱ/Ⅲ).Methods Siewert type Ⅱ/Ⅲ AEG cases performed either PG with esophagogastric anastomosis or TG with Roux-en-Y esophagojejunal reconstruction between January 2006 and December 2009 at West China Hospital of Sichuan University were analyzed retrospectively.Patients were followed up by telephone at six months or more after the surgery and QLQ was assessed by EORTC QLQ-C30 and QLQ-STO22 questionnaires.Results A total of 98 cases were Siewert type Ⅱ/Ⅲ AEG with 30 dead and 8 lost to follow up.Data from 40 cases in PG group and 20 in TG group were analyzed.There were no significant differences of baselines between two groups related to sex, age, tumor size, TNM stage (AJCC, 6th version) or hospital stay after surgery.TG group scored better than PG group in global health status without significant difference (P=0.072).PG group reported worse scores than TG group with respect to reflux symptoms, dysphagia, eating restrictions, nausea and vomiting, appetite loss, taste abnormality, social functioning and insomnia (P＜0.05).Moreover, TG group scored worse than PG group regarding to dyspnoea (P=0.027).Conclusion Siewert type Ⅱ/Ⅲ AEG patients treated by TG have a better QLQ than that of PG, especially on the aspects of reflux controlling and appetite improvement.关键词
食管胃结合部腺癌/全胃切除术/近端胃切除术/生活质量分类
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代斌,陈佳平,潘琳,杨晨,刘杰,陈心足,杨昆,胡建昆,张波,陈志新..食管胃结合部腺癌病人行近端与全胃切除术后生活质量比较[J].中国实用外科杂志,2011,31(2):147-149,3.
