林产化学与工业2011，Vol.31Issue(1)：86-90,5.
茴香脑衍生物的合成工艺研究
Study on Synthesis of Anethole Derivatives
姜萍 1李海玉 1米伟1
作者信息
- 1. 南京林业大学化学工程学院,江苏南京,210037
- 折叠
摘要
Abstract
Epoxidation of anethole with H2O2 could have 91％ yield of 2- (4-methoxyphenyl) -3-methyloxirane.The effects of the ratio of CH3CN/CH3OH, molar ratio of anethole and H2O2, dosage of catalyst, reaction temperature and reaction time on the yield were investigated.The results showed that the volume of CH3CN/CH3OH was 1∶ 5, the molar ratio of anethole and H2O2 was 1∶ 2.5, the molar ratio of anethole and anhydrous sodium carbonate was 1∶ 0.8, reaction temperature was room temperature and reaction time was 27 h.Then, reduction of 2-(4-methoxyphenyl)-3-methyloxirane with lithium aluminum hydride was used to obtain 1-(4-methoxyphenyl)-2-propanol.By single factor experiment, the results showed that the optimized conditions were as follows: ether as the best solvent, molar ratio of raw material to reducing agent was 1∶ 1.5, reaction temperature at room temperature and reaction time 1 h.The structures of the two compounds were characterized by GC-MS and IR.关键词
茴香脑/2-(4-甲氧基苯基)-3-甲基环氧乙烷/1-(4-甲氧基苯基)丙-2-醇/氢化铝锂Key words
anethole/ 2 - (4-methoxyphenyl) -3 -methyloxirane/ 1- (4 -methoxyphenyl) -2-propanol/ lithium aluminum hydride分类
化学化工引用本文复制引用
姜萍,李海玉,米伟..茴香脑衍生物的合成工艺研究[J].林产化学与工业,2011,31(1):86-90,5.
