摘要
Abstract
A convenient and industrializable new method of synthesizing 1,8-octanediol was studied.1,8-Octanedioic acid dimethyl ester was obtained at high yield, using hexamethylene dicyanide and methanol as raw material catalyzed by concentrated sulfuric acid, followed by the reduction of 1,8-octanedioic acid dimethyl ester via sodium borohydride in a NaBH4-methanoltetrahydrofuran solvent system to obtain 1,8-octanediol.Effects of the amount of NaBH4 and reaction time on the overall yield of 1,8-octanediol were investigated.The optimum reaction conditions were as follows: molar ratio of NaBH4 to 1,8-octanedioic acid dimethyl ester 5∶5.1, reaction time 8.5 h, the yield of 1,8-octanediol was 97.2 ％.关键词
1,8-辛二醇/辛二酸二甲酯/硼氢化钠-甲醇-四氢呋喃体系/合成Key words
1,8-octanediol/ octanedioic acid dimethyl ester/ NaBH4-methanol-tetrahydrofuran system/ synthesis分类
化学化工
