临床与实验病理学杂志2011，Vol.27Issue(3)：253-256,4.
结节性筋膜炎50例临床病理特征
Clinicopathologic features of nodular fasciitis:an analysis of 50 cases
黄传胜 1匡忠生 2陈文静 3赖日权 4张江宇3
作者信息
- 1. 广东省阳春市第一人民医院病理科,529600
- 2. 广州中医药大学第一附属医院病理科,广州,510405
- 3. 广东省妇幼保健院/广州医学院附属省妇儿医院病理科,广州,510010
- 4. 广州军区总医院病理科,广州,510010
- 折叠
摘要
Abstract
Purpose To study the climcopathologic characteristics and differential diagnosis of nodular fasciitis ( NF ). Methods 50cases primarily diagnosed as NF were investigated with clinical data analyses, light microscopy and immunochemistry, and the litera tures were also reviewed. Results Among 50 cases. 43 cases were correct. but 7 cases should he classified as other soft tissu tumors. Among 43 cases, 26 cases were males and 17 were females. with age ranging from 18 to 56 years ( mean 32. 5 years ). The le sions occurred in any part of the body, most commonly in the upper extremity ( 20 cases,46. 5％ ). followed by trunk ( 9 cases20. 9％ ). head and neck ( 8 cases. 18. 6％ ), and lower extremity was uncommon ( 6 cases, 13. 9％ ). Clinically, NF grew rapidl and often was solitary and small in size. and no recurrence or metastasis after operation. Histopathologically, NF was composed of plump fibrohlasts or myofihroblasts. which often arranged in c-shaped, fascicles or atypical storiform pattern , no pleomorphic cell could seen with more mitoses. The lesions contained loose and myxoid stroma. abundant vessels . extravagated red cells and irregular cranny 7 cases of NF should be diagnosised as myxofihrosarcoma, myxoid liposarcoma. low-grade fibromyxoid sarcoma, palisading fibrous his tiocytoma, cellular fibrous histiocytoma, dermatofibroma and abdominal fibromatos respectively. Immunophenotyping of 11 cases dem onstrated that tumor cells were positive for vimentin, SMA and MSA, but negative for CK, desmin, CD34 and[3-catenin. Conclusion NF is a benign, pseudosarcomaous tumour, which is composed of plump fibroblasts or myofibroblasts. It is important to make a diag nosis in comhination with the clinical and histological features. Overdiagnosis and underdiagnosis should be avoided.关键词
结节性筋膜炎/临床病理学/鉴别诊断分类
医药卫生引用本文复制引用
黄传胜,匡忠生,陈文静,赖日权,张江宇..结节性筋膜炎50例临床病理特征[J].临床与实验病理学杂志,2011,27(3):253-256,4.
