中国药房2011，Vol.22Issue(1)：92-93,2.
2例肌苷葡萄糖注射液配药后不明絮状物的红外光谱分析
Infrared Spectrum Analysis of the Unknown Floss of in Inosine Glucose Injection
李湘晖 1田甜 2许世伟 1杜智敏1
作者信息
- 1. 哈尔滨医科大学附属第二医院药学部,哈尔滨市,150086
- 2. 黑龙江省普通高等学校药物研究重点实验室,哈尔滨市,150086
- 折叠
摘要
Abstract
OBJECTIVE: To analyze the unknown floss of Inosine glucose injection in 2 cases during drug dispensing. METHODS: The unknown floss was isolated from mixture of lnosine glucose injection with Acyclovir injection and mixture of Inosine glucose injection with reduced glutathione. Isolated unknown floss was analyzed by infrared spectroscopy (IR) after cold drying. Results of IR were compared with SDBS (Spectral Data Base System) in terms of IR peak, peak shape and relative peak density to confirm whether the unknown floss was homogenous material or not and analyze its reason. RESULTS: The floss was not inosine or reduced glutathione or acyclovir. It was most likely a kind of bacteria. CONCLUSION: For such biological drugs of Inosine glucose injection, appearance should be observed carefully before clinical utilization.关键词
肌苷葡萄糖注射液/还原型谷胱甘肽/阿昔洛韦/配药/絮状物/红外光谱分析分类
医药卫生引用本文复制引用
李湘晖,田甜,许世伟,杜智敏..2例肌苷葡萄糖注射液配药后不明絮状物的红外光谱分析[J].中国药房,2011,22(1):92-93,2.
